https://microtubule-receptor.c....om/index.php/plant-l
Here we report that the elevated expression of lymphoid enhancer binding factor 1 (Lef1) is associated with the TNM (tumor- node-metastasis) phase of gastric cancer tumors. Later, 2,4-diamino-quinazoline (2,4-DAQ), a selective inhibitor of Lef1, had been identified to suppress the appearance of Wnt/β-catenin target genes such as AXIN2, MYC and LGR5 and result in the suppression of gastric cancer tumors cell growth through the apoptotic path. The 2,4-DAQ also exhibited an inhib
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