https://www.selleckchem.com/products/sp2509.html
The term "age-associated B cells" (ABCs) refers to a heterogeneous B cell subset (CD19+,CD21-, CD11c+,T-bet+) which is expanded in the elderly, but also accumulates prematurely in patients with autoimmune disorders and/or infectious diseases. In healthy individuals, ABCs represent a low prevalence population that positively impacts immunosenescence. In autoimmunity and infections though, ABCs expand dramatically and produce high titers of antibodies, thus playing a role in the regulation of humoral responses. Despite the fact that these
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