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First Line Treatment For ADHD in Adults Some people with ADHD are able to use medications to manage their symptoms. Stimulants such as methylphenidate or amphetamine are used to increase brain activity in areas that regulate attention and behavior. Other medications, like the non-stimulant atomoxetine, and other antidepressants, work differently but are also efficient. Regular visits to the GP are recommended for people who take medication. They can adjust dosages and check for body reactions. Medication For adults, medication is often the first line treatment fo