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The use of selective leukotriene D4 receptor antagonists, targeting purinergic signaling as a therapeutic approach and glutamine supplementation may decrease the severity and mortality of COVID-19. A temporal relationship between hidradenitis suppurativa (HS) and obesity has not been established. To compare baseline body mass index (BMI) and change in BMI for patients with HS and controls before and after diagnosis. We performed a retrospective case-control analysis of 1284 patients with HS and controls matched for age, sex, race and calen