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Hyperthyroidism and PD may share common manifestations. After excluding the first year of observation, a similar result is obtained (HR 2.57, 95% CI 1.61-4.01). Also, this study found that older age (HR 3.74-8.53), more comorbidities (HR 1.58-1.63), and specific comorbidities (brain injury (HR 1.57) and cerebrovascular disease (HR 3.44)) were associated with an increased risk of developing PD. Patients with hyperthyroidism have an increased risk of developing PD. Additional prospective clinical studies are warranted to examine the relat