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The results suggested that fucoidan is capable of inducing protective activity against AFB1 toxicity in Nile tilapia by enhancing the serum biochemical and tissue antioxidant responses of fish.The present work represented first study of the spatio-seasonal distribution of the multi-elements in the suspended particulate matter (SPM) of the tropical Hooghly river estuary (HRE), eastern part of India. The high load of SPM (20-3460 mg/l) might have induced negative impact on the phytoplankton density. The relative abundance of the studied