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B; si-CON scramble control siRNA; TFEB transcription factor EB; TFEB [Δ60] TFEB cleavage fragment that lacks the first 60 amino acids; VP1 viral capsid protein 1.Overutilization of tests and treatments is a widespread problem in contemporary heath care, and laboratory medicine is no exception. It is estimated that 10-70% of laboratory tests may be unnecessary, with estimates in the literature varying depending on the situation and the laboratory test. Inappropriate use of laboratory tests can lead to further unnecessary testing, adverse ev