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ADHD Medication Medication can help adults and children to focus more effectively, calm down and manage their urges. Most people suffering from ADHD report that their symptoms improve when they take medication. prescribed drugs for ADHD work by increasing levels of norepinephrine and dopamine in the brain. They're available as immediate-release tablets (small doses taken 2 to 3 times per day) or extended-release formulas with a long-acting mechanism that build in the body over a period of time. Stimu