Mesothelioma Diagnosis A doctor can identify the condition by physical exam, imaging tests and lab work. Doctors can also conduct biopsy, which entails the removal of tissue and examination under a magnifying lens. A chest X-ray, also known as a CT scan, is used to guide the needle through the lung's lining. The procedure is not invasive and could have the potential of revealing false-negative results. Diagnosis Mesothelioma is a rare cancer that is why it takes a while to determine an official diagnosis. Your doctor will begin by taking your