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ic mechanism. Coronavirus disease 2019 is an emerging highly communicable disease. Nosocomial transmission needs to be prevented through the implementation of stringent screening and infection control measures. The objective of the study is to estimate the prevalence of severe acute respiratory syndrome- coronavirus 2 (SARS-CoV-2) infection among health care workers (HCWs) post quarantine period. This is a prospective, observational study conducted at a teaching University hospital in Alkhobar, Saudi Arabia, during the period between M