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According to a pilot study we picked from 1016 successive patients known our Centre for 'difficult-to-treat' high blood pressure individuals with RH, for an observational prospective cohort study. We excluded those non-adherent to therapy (by healing medication monitoring) and those with pseudo-RH (by 24-h BP monitoring), which left 110 customers which found the European community of Cardiology/European Society of Hypertension (ESC/ESH) 2013