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ng the molecular mechanisms of viral replication and pathogenicity, and will also lead to the development of new countermeasures against BRDC. Copyright © 2020 American Society for Microbiology.The invariant natural killer (iNKT) cells are among the first innate immune cells to elicit early protective immunity that control invading viral pathogens. The role of iNKT cell subsets, iNKT1, iNKT2, and iNKT17, in herpes immunity remains to be fully elucidated. In this study, we examined the protective role of corneal-resident iNKT cell subsets