https://www.selleckchem.com/pr....oducts/Paclitaxel(Ta
Streptococcus sanguinis is an oral commensal bacterium, but can colonize pre-existing heart valve vegetations if introduced into the blood stream, leading to infective endocarditis. Loss of Mn- or Fe-cofactored virulence determinants are thought to result in enfeeblement of this bacterium. Indeed, intracellular Mn accumulation mediated by the lipoprotein SsaB, a component of the SsaACB transporter complex, has been shown to promote virulence for endocarditis and O2 tolerance. To delineate intracellular metal-ion abundance and
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