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IgE to α-Gal is a cause of mammalian meat allergy and has been linked to tick bites in North America, Australia, and Eurasia. Reports from the developing world indicate that α-Gal sensitization is prevalent but has been little investigated. We sought evidence for the cause(s) of α-Gal sensitization and lack of reported meat allergy among children in less developed settings in Ecuador and Kenya. IgE to α-Gal and total IgE were assessed in children from Ecuador (n= 599) and Kenya (n= 254) and compared with children with (n= 42) and withou
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