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The sheer number of the FosB+ cells had been substantially higher in limited sciatic nerve ligation-sedentary mice compared to Sham and Naive mice, whereas VR substantially suppressed the FosB+ cells within the vHPC-CA1. Furthermore, VR notably enhanced the proportion of activated PV+ and SOM+ interneurons in the vHPC-CA1, and tracer experiments suggested that approximately 24% of neurons projecting from the vHPC-CA1 to the basolateral nucleus of amygdal