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BACKGROUND This study assessed the impact of contact lens wear on retinal spectral domain optical coherence tomography (SD-OCT) image quality and macular thickness measurements, among subjects with myopia. METHODS This was a prospective study including 34 subjects (26.59 ± 3.19 years) with myopia or myopic astigmatism. Twelve were imaged wearing spherical soft contact lenses, eight non-contact lens wearers were imaged with a plano soft contact lens, and 14 with significant astigmatism were fitted with a rigid gas permeable (RGP) contac
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