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01). Cachexia was positively associated with depression (unstandardised coefficient ( )=2.123, p0.001) and anxiety ( =1.123, p=0.024), and had a negative relationship with PF, CF, EF, SF and overall QoL (all 0, all p0.05). Cachexia was associated with greater depression and anxiety and poorer QoL in patients with cancer, which emphasised the importance of timely identification and management of cachexia to improve the psychological problems and QoL among patients with cancer. Cachexia was associated with greater depression an