https://www.selleckchem.com/pr....oducts/dinaciclib-sc
In vitro bone formation by mesenchymal stromal cells encapsulated in type-1 collagen hydrogels is demonstrated after a 28-day in vitro culture period. Analysis of the hydrogels is carried out by X-ray micro computed tomography, histology and immunohistochemistry, which collectively demonstrates that bone formation in the hydrogels was quantifiably proportional to the initial collagen concentration, and subsequently the population density of seeded cells. This was established by varying the initial collagen concentration at