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Moreover, a discussion on the current existing problems of RM-ERMs provides important tips and suggestions for future research on RM-ERMs.Fenpiclonil is an agricultural phenylpyrrole fungicide, which raise the concern about its ecotoxicological effects. In this paper, we investigate the indirect photochemical transformation mechanisms, environmental persistence and eco-toxicity of fenpiclonil initiated by various active oxidants (1O2, •OH and SO4•‾) in aquatic environments. The results shown that 1O2 can react with pyrrole ring by cycloa