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63; 95% confidence interval, 0.48-0.84; P = 0.002). On multivariate Cox proportional hazard model analysis, age less then 65 years, Child-Pugh class A, and coverage of the entire drainage area were independent protective factors. Child-Pugh worsened in 11 (4.2%) patients in the covered group compared to 18 (6.7%) patients in the noncovered group. Conclusion RFA covering the complete drainage area improved overall survival without decreasing liver function.Hepatocellular carcinoma (HCC) can de novo develop in patients with chronic hepati
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