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ated with the height standard deviation score (r=0.255; p less then 0.05), but was not correlated with serum MKRN3 level or the others. Conclusion Although serum NPTX1 level was independent of serum MKRN3 level, the possibility they might be involved in the progression of puberty or CPP remains. Further research is needed to determine their role in the hypothalamus. Hyperammonemia in a newborn is a serious condition, which requires prompt intervention as it can lead to severe neurological impairment and death if left untreated. The most c