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In this study, a thioxanthone derivative, 2-Thioxanthone Thioacetic Acid (TXSCH2COOH) was used to analyze the type of binding to calf thymus DNA in a physiological buffer (Tris-HCl buffer solution, pH7.. Several spectroscopic techniques were employed including UV-Vis absorption and fluorescence emission spectroscopy and viscosity measurements were also used to clarify the binding mode of TXSCH2COOH to ct-DNA. The intrinsic binding constant Kb of TXSCH2COOH-ct-DNA was found as 2.5 × 103 M-1 from the absorption studies. Increasing of flu