https://www.selleckchem.com/pr....oducts/Cisplatin.htm
Background Fibroblast growth factors (FGFs) are heparin-binding proteins involved in a variety of biological processes, and part of them may act through binding with cell membrane receptor FGFR2. Objectives To clarify the role and mechanisms of FGFR2 signaling in tubular cell survival and acute kidney injury (AKI). Method In this study, kidney ischemia/reperfusion (IR) or cisplatin injection was used to induce AKI in mice. Results In the kidneys after IR or cisplatin injection, the expression of FGFs and Erk1/2 phosphorylation were el
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