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However, the distances from the distal margin of mental foramen was significantly lower in Class I patients (P less then 0.05). CONCLUSION In case of deviated skeletal development, position and size of anatomical structures can vary significantly. Prognathic mandibles has increased risk of neurovascular complications and bad splits. Morphologic data provided in this study may help practitioners for better surgical planning to reduce complications. Across species, nicotine can produce robust discriminative stimulus (DS) effects, as with ot