https://www.selleckchem.com/pr....oducts/ldc203974-imt
Multipotent bone marrow stromal cells (BMSCs) are adult stem cells that form functional osteoblasts and play a critical role in bone remodeling. During aging, an increase in bone loss and reduction in structural integrity lead to osteoporosis and result in an increased risk of fracture. We examined age-dependent histological changes in murine vertebrae and uncovered that bone loss begins as early as the age of 1 mo. To identify the functional alterations and transcriptomic dynamics of BMSCs during early bone loss. We collected B