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001-0.05 for all cases). Furthermore, GC/MS analysis revealed that essential oils of mainly consisted of β-caryophellene, α-pinene and limonene. Our findings demonstrated that extracts can exert cytotoxic effects against GBM U87 cell line in a time- and concentration-dependent manner, and these effects may be mediated through intracellular ROS accumulating. However, further studies should be performed to confirm the efficacy and exact mechanism of action of the extracts. Our findings demonstrated that D.kotschyi extracts can exert cytoto