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05). Furthermore, fullerene supplementation decreased serum concentrations of inflammatory cytokine and lipopolysaccharide (LPS; a penetrability marker) compared to the DON-challenged group (p less then 0.05). The current study suggests that fullerene C60 improves intestinal antioxidant status against DON-induced oxidative stress in vitro and in vivo.In this study, Fe3O4-ZrO2 functionalized with 3-aminopropyltriethoxysilane (Fe3O4-ZrO2@APS) nanocomposite was investigated as a nanoadsorbent for the removal of Cd(II), Cu(II), Mn (II) and