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[This corrects the article DOI 10.2147/JPR.S232132.]. The study was designed to mine the expression and roles of IQGAP3 in clear cell renal cell carcinoma (ccRCC). Expression profiles and clinical information were obtained from the Cancer Genome Atlas (TCGA) to estimate IQGAP3 expression in ccRCC, its relationship with patients' clinicopathological variables and prognosis, and the potential biological mechanisms. IQGAP3 was highly expressed in ccRCC and indicated advanced clinical outcome and poor prognosis. IQGAP3 affected the progress