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05). The positive rates of pre-CEA and pre-DDC increased with the increase of TNM stage, deepening of invasion, lymph node metastasis, and serosal invasion (all P0.05), but had no correlation with tumor location, size, degree of differentiation, nerve invasion, and vascular invasion (all P0.05). The disease-free survival in the combined positive patients was lower than that in the negative patients. Laparoscopic radical gastrectomy for GC is safe and feasible, without increasing the risk of PM. The PM of GC may be associated wit