https://www.selleckchem.com/pr....oducts/pitstop-2.htm
Finally, we interrogate how mitophagy affects tissue atrophy during cancer cachexia and therapy responses in the clinic.Many tumors are now understood to be heterogenous cell populations arising from a minority of epithelial-like cancer stem cells (CSCs). CSCs demonstrate distinctive metabolic signatures from the more differentiated surrounding tumor bulk that confer resistance to traditional chemotherapeutic regimens and potential for tumor relapse. Many CSC phenotypes including metabolism, epithelial-to-mesenchymal transition, cellu