https://www.selleckchem.com/pr....oducts/pirfenidone.h
In summary, we found that LincQ specifically interacts with Sox2 and contributes to the maintenance of pluripotency, highlighting the critical role of lincRNA in the pluripotency regulatory network. © AlphaMed Press 2020 SIGNIFICANCE STATEMENT This study shows that the long intergenic noncoding RNA LincQ is critical for embryonic stem cell (ESC) pluripotency maintenance. LincQ is highly expressed in ESCs and is downregulated during differentiation. Further, its inhibition leads to ESC differentiation. LincQ binds to Sox2 to regulate
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