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Medications For ADHD and Anxiety Certain stimulants can trigger adverse effects, like an upset tummy and tics as well as changes in blood pressure and heart rate. These effects usually occur during the first few weeks of taking the medication. They will pass by themselves after a few weeks. Nonstimulant ADHD medications such as atomoxetine (Strattera) are able to have a shorter time to take effect than stimulants, but they are effective and can last up to 24 hours. Non-Stimulant Medication Medicines are the most effective treatment for the condition known as