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Nevertheless, there are numerous impediments towards the growth of secure and efficient anticancer drugs. The purpose of the present study was to assess the effectation of aviculin isolated from Lespedeza cuneata (Dum. Cours.) G. Don. (Fabaceae) on MCF-7 human being breast cancer cells and discover the fundamental device. Making use of the bioassay-guided isolation by water-soluble tetrazolium salt (WST-1)-based Ez-Cytox assay, nine compounds (four lignan glycosides (1-4), three flavonoi