https://www.selleckchem.com/pr....oducts/NVP-ADW742.ht
A human mAb isolated from a COVID-19 donor defines a protective cross-neutralizing epitope promising for pan-β-CoV vaccine strategies.Severe COVID-19 has been associated with T cell lymphopenia 1,2, but no causal effect of T cell deficiency on disease severity has been established. To investigate the specific role of T cells in recovery from SARS-CoV-2 infections we studied rhesus macaques that were depleted of either CD4+, CD8+ or both T cell subsets prior to infection. Peak virus loads were similar in all groups, but the resolution