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Chinese queer parents' participation in assisted reproduction has destabilised the dominant hetero-reproductive family matrix while simultaneously contributing to stratified reproduction.Prime editors (PEs) were developed to induce versatile edits at a guide-specified genomic locus. With all RNA-guided genome editors, guide-dependent off-target (OT) mutations can occur at other sites bearing similarity to the intended target. However, whether PEs carry the additional risk of guide-independent mutations elicited by their unique enzymatic m