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Here, the writers report an uncommon ocular adverse impact after periocular Botulinum Toxin-A injection for hemifacial spasm. Three days after the injection, facial spasm had been relieved, but the patient had dimness of eyesight OS. Examination revealed corneal edema, anterior-chamber response, keratic precipitates, and elevated intraocular stress in OS suggesting reactivation of herpes simplex viral endotheliitis with trabeculitis. The scenario ended up being effectively treated with