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ADHD Medications For Adults Stimulants help adjust levels of chemical messengers in the brain that regulate attention. They are the first line of treatment for treating ADHD. Although they are not habit-forming, they can cause side effects such as headaches and sleep problems. Your doctor could prescribe Guanfacine (brand names Tenex and Intuniv) or clonidine (Catapres) to decrease hyperactivity and impulsivity. These medications are more effective than stimulants. Stimulants The most