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coli) were investigated at 1, 2, and 7 days following IS in ten male sheep. We found an increase of both APPs as well as a decrease of all anti-E. coli antibodies within 48 h following IS. This may indicate an early systemic APR and increased IP, and underlines the importance of the increasingly recognized gut-brain axis and of intestinal antigen release for systemic immune responses in acute and subacute stroke stages. Copyright © 2020 Ferrara, Zeisig, Pietsch, Rütten, Dreyer, Pieper, Schatzl, McLeod, Barthel, Boltze, Schrödl and Nitzs
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