https://www.selleckchem.com/products/Y-27632.html
Protein kinase B (AKT) PI3K / AKT / mTOR signaling pathways play a crucial role in the modulation of cell survival, proliferation, metastasis, metabolism, angiogenesis, and apoptosis. The AKT family consists of three isoforms AKT1, AKT2, and AKT3. Moreover, it has high sequence homology in the kinase domain and has similar substrate specificity to other members of AGC protein kinase. Recent studies have shown that AKT signals disappear in some tumors. Overexpression and activation of AKT are not sufficient to induce the phenotype of mal