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This article is shielded by copyright. All rights reserved.OBJECTIVE This meta-analysis ended up being performed to systematically assess the effectiveness of hyaluronidase coupled with corticosteroids weighed against various other drugs in increasing optimum mouth opening and alleviating the burning feeling in patients with oral submucous fibrosis (OSF). METHODS PubMed, Embase, Web of Science, plus the Cochrane Library were looked. RevMan 5.3 software ended up being utilized for the meta-analysis. O