https://www.selleckchem.com/pr....oducts/eflornithine-
Background Aquaporins (AQPs) are water channel proteins robustly presenting in the central nervous system (CNS). Increasing evidence suggests the crucial role of AQP1 in the pathogenesis of CNS injury but scarce data are provided for the potential role of AQP1 in Alzheimer's disease (AD). Thus, the present study aimed to investigate the effects of AQP1 on cognitive function in a mouse model of AD. Methods A mouse model of AD was established by using the β-amyloid isoform Aβ1-42, and then assessed by the step-t