https://vinblastineinhibitor.c....om/genomic-as-well-a
The observations demonstrated that miR-200 and GRHL2 had been overexpressed into the serum of NAFLD patients and mice, while SIRT1 ended up being poorly expressed. GRHL2 positively regulated miR-200 by binding to miR-200 promoter area, which adversely targeted SIRT1. The inhibition of miR-200 and GRHL2 or SIRT1 overexpression lowered HA and LN in mouse liver tissue, occludin and ZO-1 in mouse small intestine muscle, TNF-α and IL-6 in mouse serum, sugar, complete cholesterol (TC), triglyceride (TG
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