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Finding the Best Medication For ADHD The most common medication prescribed for ADHD is stimulants. They include methylphenidates and amphetamines. Short-acting stimulants are effective in less than one hour and must be taken several times a day. Long-acting stimulants last up to 16 hours and are taken every day. Your doctor might prescribe antidepressants and other types of drugs "off-label" to treat ADHD symptoms. These drugs are approved to treat conditions like depressi
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