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Synaptic cooperation and competitors can see whether two events , separated with time, tend to be connected or whether a specific occasion is chosen for storage. The rules that determine whether synapses cooperate or compete tend to be unknown. We unearthed that synaptic cooperation and competition, when you look at the Los Angeles, are based on the temporal series of cortical and thalamic stimulation and that the effectiveness of the synaptic tag is modulated by the endocannabinoid signaling. This modulation is particularly efficient i