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The rapidly progressive fibrosis in BA, represented by fibrosis grade of the intraoperative LB, correlated significantly to SOX9-DR and HPC-DR at the diagnostic (r=0.420, P=0.003 and r=0.405, P=0.004, respectively) and the intraoperative (r=0.460, P=0.001 and r=0.467, P=0.001, respectively) biopsy. On the other hand, fibrosis, SOX9-DR, and HPC-DR were significantly lower in non-BA cases at a comparable age (P0.001, P=0.006, and P=0.014, respectively). Fibrosis in BA is rapidly progressive within a short time and is significantly co