https://www.selleckchem.com/pr....oducts/guanosine-5-t
Excellent concordance was found for most genes, and most discordant calls occurred at VAF 1%. In longitudinal samples from progressing patients with endocrine resistance, we detected consistent alterations in sequential samples, most commonly in ESR1 and PIK3CA. This study shows that both ultra-deep next-generation sequencing (NGS) technologies can detect genomic alternations even at low VAFs in plasma samples of mBC patients. The strong agreement of the technologies indicates sufficient reproducibil
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