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Treatment of Adult ADHD The majority of people with ADHD suffer from mental health issues like anxiety or substance abuse disorders, or depression. These conditions can affect the effectiveness of ADHD medications. Psychological counseling can assist patients in learning to manage their symptoms and improve relationships. Counseling can include cognitive behavioral therapy, which teaches patients to recognize and change negative thoughts and behavior. Medication Medication is a powerful treatment for adults with ADHD. can improve concentration and ease symptoms,