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Health Issues That Affect German Shepherd Life Expectancy German Shepherds are in their prime between the ages of 2 and 6 years old. They are at their best in terms of physical fitness and mental sharpness. Their large size makes them at a higher risk of developing cancer muscular and skeletal issues, as well as other health conditions that can impact lifespan. Working line German Shepherds often have more active lives than their show line counterparts. They require a nutritious diet to m