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New Zealand rabbits had been externally administrated rh-aFGF carbomer 940 hydrogel at a regular dosage of 900 IU/cm2, 1,800 IU/cm2, and 3,600 IU/cm2 for 28 days. Lyophilized rh-aFGF agent was utilized because the good control team. General behavior, serum biochemistry, epidermis discomfort, immunogenicity, immunotoxicity, and histopathology had been analyzed at designated time points. Outcomes disclosed that diet, weight, body's temperature, heart rate, and attention exa