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In this work, the stem bark (ZM) and good fresh fruit extracts (ZMFT) of Zanthoxylum gilletii had been put through line chromatography and afforded lupeol (1), 2,3-epoxy-6,7-methylenedioxyconiferyl alcohol (3), nitidine chloride (4), nitidine (7), sucrose (6) and sitosterol-β-D-glucopyranoside (2). The compounds had been characterized using MS and NMR spectral data. The examples had been examined for antimicrobial, antibiofilm and anti-quorum sensing activities. Highest antimicrobial task w